Category BMED L06 Biocompatibility of 3-D Printed Plastics with Staphylococcus

epidermidis in Hy

Abstract This experiment is to evaluate the biocompatibility of two polymer

materials, carboxymethylcellulose and poly(lactic acid) by measuring

bacterial growth on the polymer surface in a hyaluronic acid solution.

Polylactic acid (PLA) along with the carboxymethylcellulose (CMC) will

be divided into six separate pieces and submerged into a hyaluronic

acid solution to resemble more of a joint area. Then bacteria will be

added to the surface of the plastics. After a few days the bacteria will

be swabbed onto new petri dishes and the bacteria colonies will be

counted, thus determining which plastic is more biocompatible. The

hypothesis was that it is expected that both polymers will exhibit

adhesion and proliferation of S. epidermidis on their surfaces. However,

due to its already present use in medical technology PLA is expected

to grow more bacteria, so PLA will be more biocompatible than CMC,

and the hypothesis was supported. PLA grew bacteria in a uniformed

way, that also covered most of the petri dish. CMC did prove to be

biocompatible but it had a more of a separated growth pattern. CMC

also absorbed the hyaluronic acid solution which would not be practical

for the long-term goal.

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Singh, D. A., About Dr Arun Pal SinghArun Pal Singh is an orthopedic

and trauma surgeon, founder and chief editor of this website. He works

in Kanwar Hospital, Hajipur, Hoshiarpur, Punjab.

Arthritis.(2017, March 15). Retrieved February 2, 2017, from

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